Active ingredients
Nonacog alfa
Indications
Hemophilia, hemophilia B
Alternative Chinese medicine
Salvia miltiorrhiza, Astragalus, Tripterygium wilfordii, Ligusticum chuanxiong, Panax notoginseng, Erigeron.
Active ingredients in Chinese medicine
Danshensu and tanshinone in Danshen have antithrombotic effects. Astragalus can comprehensively improve the clinical symptoms of PH. Triptolide can improve pulmonary vascular inflammation and thereby improve pulmonary fibrosis, thereby delaying disease progression. Chuanxiong also has the same effect. Breviscapine , Panax notoginseng saponins, especially the components of Panax notoginseng saponins can inhibit vascular remodeling, thereby preventing and delaying the development of the disease.
Possible side effects
The most side-effect drug in the prescription is Tripterygium wilfordii, which is a large toxic traditional Chinese medicine, which can cause gastrointestinal reactions such as loss of appetite, upper abdominal discomfort, nausea, vomiting, abdominal pain, diarrhea, etc., which can cause damage to the reproductive system. Long-term use will inhibit reproduction. It can cause skin and mucosal damage, induce acute renal insufficiency, acute toxic hepatitis, destroy red blood cells, cause progressive anemia, leukopenia, diffuse intravascular coagulation, acute aplastic anemia, etc., affect the cardiovascular system, Damage to the central nervous system, improper application may cause death.